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Ferrara is situated in the valley of the river Po in Northern Italy, south of Padua and Venice and north of Bologna, in the Emilia-Romagna region. It is convenient for a day tour from each of these three cities. It is not known for certain when Ferrara was founded. It was first mentioned in a 8th-century document as part of the Ravenna Exarchate. From the beginning of the 13th to the end of the 16th century, Ferrara was ruled by the Este family who were responsible for the construction of many of the monuments we admire today. They were also patrons of art, literature and music, and artists such as Leonardo Da Vinci, Titian and Raphael, as well as Petrarch and Antoine Brumel enjoyed their support. Alfonso I (1486-1534) is worth mentioning not only because he commissioned a series of works to Titian but also as the third husband of the notorious Lucrezia Borgia. The House of Este came to an end in 1598, and Ferrara was enlisted among Papal states, saw Austrian occupation in the 19th century, and finally became part of the Kingdom of Italy.