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Genoa is situated in northern Italy, in the region of Liguria, on the Mediterranean Sea. It has been a lively port since the time of the Etruscans, under Greek control from the 6th c. B.C., then as part of the Roman Empire. For a while, it was overshadowed by neighbouring Savona and, after the fall of the Roman Empire, saw occupation by Ostrogoths and Longobards and attacks by Arab pirates in the 10th century. It then emerged as an independent city state, one of the "maritime republics" with a powerful navy, flourished thanks to shipbuilding, banking and trade, played an important role in the Crusades and established colonies in Sicily, Northern Africa and the Middle East. In the 13th century, Genoa was a leading naval power in the Mediterranean, having defeated its main rivals Pisa at Meloria (1284) and Venice at Curzola island (1298). A plague epidemic popularly known as the Black Death struck the city in the mid-14th century. Economic recovery was observed only in the 16th century, at the time of Cristopher Columbus' expedition and Andrea Doria, and a number of renowned artists such as Caravaggio, Van Dyck and Rubens were attracted to the Superba. In newer times, Genoa was involved in the struggles of the Risorgimento, and its was from there that Giuseppe Garibaldi began his campaign against Sicily with his thousand volunteers in 1860.