Uffizi Gallery (Galleria degli Uffizi)
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A 16th-century edifice by Giorgio Vasari, this palazzo is among Florence's principal landmarks. Having served as an administrative office building, a Tribunal and a state archive, the building was gradually converted into a museum to hold the Medici collections of art. The museum first 

Museum of the History of Science (Museo di Storia
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Installed in an 18th-century building, this museum combines classic interiors with displays of the cutting-edge science gadgets. Here one can spot an entire section dedicated to Galileo, with some of the original instruments of the mathematician and astronomer who spent a significant part of his 

Horne Museum
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Named after English collector, Herbert Horne, this museum is located in a stately mansion that used to be the former property of the Alberti family. In the late 15th Century the building's design was altered by Simone del Pollaiuolo, and it was into that mansion that Horne moved towards the late